From the North: follow 108 South into Exeter. At lights, turn right onto High Street (which then turns into Water Street, then Main Street) Follow the road through downtown. Just past Phillips Exeter Academy, you will see it on the left, 40 Main Street.

From the East: Take 101 West to the 108 Exit; take 108 South into Exeter. Turn right onto High Street (Which turns into Water Street, then Main Street). Follow Main Street through downtown. Just past Phillips Exeter Academy, you will see it on the left.

From the West: Take 101 East to Exit 9, Route 27. Turn right onto Route 27 and proceed for almost 2 miles. After the railroad tracks, there is a sharp bend in the road, the school is around that corner on the right.

From Boston: Follow I95 to 101 West. Take 101 West to Exit 11 (Route 108); take 108 South into Exeter. Turn right at the light that dead ends and follow the road through downtown (the road name changes from High Street to Water Street to Main Street) onto Main Street. and up the hill. Main Street School is at the top of the hill on the left.